Out-Licensed Compounds/Programs

Compound Principal Target Partner Stage of Development

XL880

VEGFR2, MET

GlaxoSmithKline
Phase 2
 

XL147

PI3K

Sanofi-Aventis
Phase 2
 

XL765

PI3K, mTOR

Sanofi-Aventis
Phase 1b/2
 

XL518

MEK

Genentech/Roche
Phase 1b
 

XL652/XL041

LXR

Bristol-Myers Squibb
Phase 1
 

XL139

Hedgehog

Bristol-Myers Squibb
Phase 1
 

XL281

RAF

Bristol-Myers Squibb
Phase 1
 

XL475

TGR5

Bristol-Myers Squibb
Preclinical
 

XL550

MR

Daiichi-Sankyo
Phase 1
 

Isoform Selective PI3Kα and PI3Kβ

PI3Kα and PI3Kβ

Sanofi-Aventis
Preclinical
 

ROR Antagonists

ROR antagonists

Bristol-Myers Squibb
Preclinical